For a successful pregnancy to occur, foreign genetic material such as the allogeneic fetus must be tolerated within the maternal host. Indoleamine 2,3-dioxygenase (IDO) is an enzyme induced by pro-inflammatory cytokines that has been shown to be key to this process. Obesity as a pro-inflammatory state is associated with poor obstetric outcomes. The primary objective of this study is to investigate the relationship between obesity and IDO activity.
Keywords: Preeclampsia, obesity in pregnancy, immunology of pregnancy, fetal tolerance
How to Cite:
Tyler, E. M. & Santillan, D. A. & Scroggins, S. M. & Devor, E. J. & Hamilton, W. S. & Hunter, S. K. & Santillan, M. K., (2015) “The relationship between obesity, pregnancy, and levels of indoleamine 2,3-dioxygenase”, Proceedings in Obstetrics and Gynecology 5(3), 1-2. doi: https://doi.org/10.17077/2154-4751.1301
Rights: Copyright © 2015 the authors