Extended Abstract

The relationship between obesity, pregnancy, and levels of indoleamine 2,3-dioxygenase

Authors: Eric M Tyler (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242) , Donna A. Santillan orcid logo (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242) , Sabrina M. Scroggins (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242) , Eric J. Devor (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242) , Wendy S. Hamilton (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242) , Stephen K. Hunter (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242) , Mark K. Santillan (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242)

  • The relationship between obesity, pregnancy, and levels of indoleamine 2,3-dioxygenase

    Extended Abstract

    The relationship between obesity, pregnancy, and levels of indoleamine 2,3-dioxygenase

    Authors: , , , , , ,

Abstract

For a successful pregnancy to occur, foreign genetic material such as the allogeneic fetus must be tolerated within the maternal host. Indoleamine 2,3-dioxygenase (IDO) is an enzyme induced by pro-inflammatory cytokines that has been shown to be key to this process. Obesity as a pro-inflammatory state is associated with poor obstetric outcomes. The primary objective of this study is to investigate the relationship between obesity and IDO activity.

Keywords: Preeclampsia, obesity in pregnancy, immunology of pregnancy, fetal tolerance

How to Cite:

Tyler, E. M. & Santillan, D. A. & Scroggins, S. M. & Devor, E. J. & Hamilton, W. S. & Hunter, S. K. & Santillan, M. K., (2015) “The relationship between obesity, pregnancy, and levels of indoleamine 2,3-dioxygenase”, Proceedings in Obstetrics and Gynecology 5(3), 1–2. doi: https://doi.org/10.17077/2154-4751.1301

Rights: Copyright © 2015 the authors

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Published on
01 Dec 2015
Peer Reviewed
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CC BY 4.0