Article
Authors: Reyhan Kaplan Hafızoğlu (Department of Obstetrics and Gynecology, Sakarya University School of Medicine, Sakarya Research and Education Hospital, Sakarya, Turkey) , Serkan Kumbasar (Department of Obstetrics and Gynecology, Sakarya University School of Medicine, Sakarya Research and Education Hospital, Sakarya, Turkey) , Bulat Aytek Şık (Faculty of Health Sciences, Aydin University, İstanbul, Turkey) , Murat Bozkurt (Department of Obstetrics and Gynecology, Sakarya University School of Medicine, Sakarya Research and Education Hospital, Sakarya, Turkey) , Mustafa Ulaş (Department of Physiology, Fırat University School of Medicine, Elazıg, Turkey) , Ayse Ender Yumru (Department of Obstetrics and Gynecology, Şişli Hamidiye Etfal Research and Education Hospital, İstanbul, Turkey) , Burcu Dinçgez (Department of Obstetrics and Gynecology, Sevket Yılmaz Research and Education Hospital, Bursa, Turkey) , Süleyman Salman (Department of Obstetrics and Gynecology, Gaziosmanpasa Taksim Research and Education Hospital, İstanbul, Turkey)
Background: In recent years the rate of cesarean section has significantly increased.To determine the efficacy of prophylactic antibiotics in reducing infectious morbidity after cesarean section.
Objectives: In our study, we aimed to evaluate the efficiency of prophylactic antibiotic administration by comparing three groups using single, multiple and no prophylactic antibiotic therapy.
Materials and Methods: Our study is a prospective, randomized controlled study including emergent cases, that developed cesarean indication while in active labor, and elective cesarean cases. A total of 90 patients were included in the study, including 30 patients who underwent cesarean delivery and did not undergo an antibiotic prophylaxis (Group 1), 30 patients who underwent a single dose antibiotic prophylaxis (Group II) and 30 patients who underwent multiple dose antibiotic prophylaxis (Group III).
Results: The incidence of wound infection was significantly higher in cases that were not using antibiotics at postoperative days 3, 5 and 7 compared to the cases using single and multiple antibiotics. There was not a significant difference between groups in terms of endometritis.
Conclusion: Administration of prophylactic antibiotics prevent wound infection but does not prevent development of endometritis.
Keywords: Antibiotic prophylaxis, infection, cesarean section
How to Cite: Hafızoğlu, R. K. , Kumbasar, S. , Şık, B. A. , Bozkurt, M. , Ulaş, M. , Yumru, A. E. , Dinçgez, B. & Salman, S. (2016) “Evaluation of the efficiency of antibiotic prophylaxis in cesarean cases”, Proceedings in Obstetrics and Gynecology. 6(1). doi: https://doi.org/10.17077/2154-4751.1309