Abstract

Zmiz1 is overexpressed in epithelial ovarian cancer and associated with p53 gene mutations

Authors: Niyati J Nadkarni (University of Iowa) , Laura M. Rogers (University of Iowa) , Megan Samuelson (University of Iowa) , Traci Neff (University of Iowa) , David P. Bender (University of Iowa) , Amina Ahmed (University of Iowa) , Koen De Geest (University of Iowa) , Anna Button (University of Iowa) , Adam Dupuy (University of Iowa) , Michael Goodheart

Abstract

Zmiz1 staining is elevated in patients with epithelial ovarian cancer. Tumors that are Zmiz1 positive are associated with mutations of the p53 gene. Zmiz1 overexpression may be associated with decreased survival in patients with epithelial ovarian cancer. Additional studies are needed to more clearly determine the role of Zmiz1 in patients with epithelial ovarian cancer.

Keywords: Zmiz1, ovarian cancer, P53 mutations

How to Cite: Nadkarni, N. J. , Rogers, L. M. , Samuelson, M. , Neff, T. , Bender, D. P. , Ahmed, A. , De Geest, K. , Button, A. , Dupuy, A. & Goodheart, M. (2011) “Zmiz1 is overexpressed in epithelial ovarian cancer and associated with p53 gene mutations”, Proceedings in Obstetrics and Gynecology. 2(1). doi: https://doi.org/10.17077/2154-4751.1108