Extended Abstract
Authors: Whitney Cowman (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa) , Sabrina Scroggins (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa) , Wendy Hamilton (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa) , Brenda Boese (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa) , Noelle C Bowdler (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa) , Mark K. Santillan (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa) , Donna A. Santillan (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa)
Obesity in pregnancy is becoming increasingly common and is associated with many pregnancy-related complications such as failed induction of labor (IOL). Leptin, an adipocytokine important in energy homeostasis, is found in higher levels in obese individuals. Leptin has also been demonstrated to have an inhibitory effect on myometrial contractility in vitro. We hypothesize that leptin may play a part in the mechanism of dysfunctional labor. Thus, we sought to compare the maternal plasma leptin levels in women that had a successful vaginal delivery post-IOL vs. those who had a C-section post-IOL.
Keywords: Obesity, induction of labor, leptin
How to Cite: Cowman, W. , Scroggins, S. , Hamilton, W. , Boese, B. , Bowdler, N. C. , Santillan, M. K. & Santillan, D. A. (2015) “Does leptin predict successful induction of labor?”, Proceedings in Obstetrics and Gynecology. 5(3). doi: https://doi.org/10.17077/2154-4751.1300