Case Report

Metastatic squamous cell carcinoma to the colon arising from a mature cystic ovarian teratoma

Authors: Jaimie Maines (Department of Obstetrics and Gynecology, Penn State Hershey Medical Center, Hershey, Pennsylvania) , Jordan Newell (Division of Anatomic Pathology, Department of Pathology, Penn State Hershey Medical Center, Hershey, Pennsylvania) , Elizabeth Frauenhoffer (Division of Anatomic Pathology, Department of Pathology, Penn State Hershey Medical Center, Hershey, Pennsylvania) , Justin Juliano (Division of Radiation Medicine, Penn State Hershey Medical Center, Hershey, Pennsylvania) , Francesca Ruggiero (Division of Anatomic Pathology, Department of Pathology, Penn State Hershey Medical Center, Hershey, Pennsylvania) , Ian Schreibman (Division of Gastroenterology, Department of Medicine, Penn State Hershey Medical Center, Hershey, Pennsylvania) , Joshua P. Kesterson (Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Penn State Hershey Medical Center, Hershey, Pennsylvania)

  • Metastatic squamous cell carcinoma to the colon arising from a mature cystic ovarian teratoma

    Case Report

    Metastatic squamous cell carcinoma to the colon arising from a mature cystic ovarian teratoma

    Authors: , , , , , ,

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Abstract

Malignant transformation of a mature cystic teratoma is extremely rare, occurring in 0.17-2% of cases.1 The most common malignant degeneration is squamous cell carcinoma (SCC) arising from the ectoderm. Approximately half of all cases of SCC of the ovary are confined to the ovary at time diagnosis.1,2 Secondary to its absolute rarity and the relative infrequency of cases with metastatic spread the optimal treatment of advanced stage disease is unknown. Outcomes for locally advanced and widespread disease have historically been very poor. Ford and Timmons recently reported on a patient with stage IIC SCC arising in a mature cystic teratoma treated with multimodal therapy who has been free of disease for more than five years.3 Herein we report on a woman with stage IIIC SCC arising within a mature cystic teratoma treated with directed chemoradiation who subsequently developed metastatic SCC to the colon.

Keywords: Squamous cell, carcinoma, teratoma

How to Cite:

Maines, J. & Newell, J. & Frauenhoffer, E. & Juliano, J. & Ruggiero, F. & Schreibman, I. & Kesterson, J. P., (2017) “Metastatic squamous cell carcinoma to the colon arising from a mature cystic ovarian teratoma”, Proceedings in Obstetrics and Gynecology 7(2), 1–6. doi: https://doi.org/10.17077/2154-4751.1342

Rights: Copyright © 2017 the authors

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Published on
01 Jul 2017
Peer Reviewed
License
CC BY 4.0