Extended Abstract
Authors: Brian M. Kilonzo (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242) , Traci Neff (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242) , Megan I. Samuelson (Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242) , Michael J. Goodheart (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242)
Granulosa cell tumors (GCT), a malignant type of sex-cord stromal tumor, account for approximately 2-5% of all ovarian malignancies. They are often identified before they have spread beyond the ovary, but advanced disease can be quite challenging to treat. Wnt signaling has been suggested to contribute to the formation of GCT. We hypothesized Wnt signaling was involved in human GCT.
Keywords: Granulosa cell tumor, ovarian neoplasms, Wnt signaling
How to Cite: Kilonzo, B. M. , Neff, T. , Samuelson, M. I. & Goodheart, M. J. (2015) “Wnt signaling in granulosa cell tumors of the ovary”, Proceedings in Obstetrics and Gynecology. 4(3). doi: https://doi.org/10.17077/2154-4751.1270