Extended Abstract
Authors: Vincent M Wagner (Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA) , Erin A Salinas (Compass Oncology, Portland, OR) , Sarah L Mott (Holden Clinical Cancer Center Biostatistics Core Alliance, University of Iowa Hospitals and Clinics, Iowa City, IA) , Wenqing Sun (Department Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA) , Michael J. Goodheart (Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Iowa Hospitals and Clinics, Iowa City, Iowa)
For patients with endometrial cancer at increased risk of perioperative morbidity, primary radiation therapy is an effective alternative treatment option. However, there has been no consensus on radiation technique and little data on outcomes. Our aim was to identify factors which determine patient selection for primary radiation, investigate treatment efficacy of radiation compared to surgical management of endometrial cancer and to evaluate different radiation modalities including external beam radiation therapy alone or with a boost of either high dose rate brachytherapy or intensity-modulated radiation therapy for differences in toxicities, recurrence-free interval, cancer-specific survival and overall survival.
Keywords: Endometrial cancer, radiation, brachytherapy, intensity-modulated radiation therapy, obesity
How to Cite: Wagner, V. M. , Salinas, E. A. , Mott, S. L. , Sun, W. & Goodheart, M. J. (2020) “Primary radiation as initial management in endometrial cancer: investigating EBRT, IMRT and HDR brachytherapy”, Proceedings in Obstetrics and Gynecology. 9(3). doi: https://doi.org/10.17077/2154-4751.1492